Mechanisms of hormonal regulation of CAD gene expression and inhibition by Aryl hydrocarbon receptor agonist in human breast cancer cells

The CAD gene is trifunctional and expresses carbamoylphosphate synthetase/aspartate carbamyltransferase/dihydroorotase, which are required for pyrimidine biosynthesis. CAD gene activities are induced in MCF-7 human breast cancer cells, and treatment of MCF-7 or ZR-75 cells with 17b-estradiol (E2) re...

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Bibliographic Details
Main Author: Khan, Shaheen Munawar Ali
Other Authors: Safe, Stephen H.
Format: Others
Language:en_US
Published: Texas A&M University 2007
Subjects:
CAD
Online Access:http://hdl.handle.net/1969.1/4935