Rational design of organophosphorus hydrolase for the degradation and detection of neurotoxic pesticides and chemical warfare agents
It is critical to consider the balance between the catalytic capabilities of an enzyme and the inherent structural stability of the protein when developing enzymes for specific applications. Rational site directed mutagenesis has been used to explore the role of residues 254 and 257 in the global st...
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Format: | Others |
Language: | en_US |
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Texas A&M University
2007
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Online Access: | http://hdl.handle.net/1969.1/5800 |