Probing the Biosynthesis and Mode of Action of Azinomycin B

Since the isolation of azinomycins A and B in 1954 from the soil bacterium, Streptomyces sahachiroi, these natural products have been synthetic targets. Both compounds exhibit in vitro cytotoxic activity at submicromolar levels and demonstrate anti-tumor activities comparable to that of mitomycin C...

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Bibliographic Details
Main Author: Kelly, Gilbert Thomson
Other Authors: Watanabe, Coran M.
Format: Others
Language:en_US
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1969.1/ETD-TAMU-2009-08-820