Probing the Biosynthesis and Mode of Action of Azinomycin B
Since the isolation of azinomycins A and B in 1954 from the soil bacterium, Streptomyces sahachiroi, these natural products have been synthetic targets. Both compounds exhibit in vitro cytotoxic activity at submicromolar levels and demonstrate anti-tumor activities comparable to that of mitomycin C...
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Format: | Others |
Language: | en_US |
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2010
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Online Access: | http://hdl.handle.net/1969.1/ETD-TAMU-2009-08-820 |