Extended Homozygosity Score Tests to Detect Positive Selection in Genome-wide Scans
Positive natural selection is recognized as the driving force underneath evolution. One of the surest signatures of recent positive selection is a local elevation of advantageous allele frequency and linkage disequilibrium (LD). This dissertation proposes a new test statistic to detect excess homozy...
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Format: | Others |
Language: | en_US |
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2011
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Online Access: | http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7687 |