Extended Homozygosity Score Tests to Detect Positive Selection in Genome-wide Scans

Positive natural selection is recognized as the driving force underneath evolution. One of the surest signatures of recent positive selection is a local elevation of advantageous allele frequency and linkage disequilibrium (LD). This dissertation proposes a new test statistic to detect excess homozy...

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Bibliographic Details
Main Author: Zhong, Ming
Other Authors: Fan, Ruzong
Format: Others
Language:en_US
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7687