Structural Studies of the Catalytic and Regulatory Mechanisms of Phenylalanine Hydroxylase

The catalytic and regulatory mechanisms of phenylalanine hydroxylase were investigated by structural studies of in this research. Phenylalanine hydroxylase (PheH) hydroxylates phenylalanine to produce tyrosine using tetrahydrobiopterin (BH4) and oxygen. The three ligands to the iron, His285, His290,...

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Bibliographic Details
Main Author: Li, Jun
Other Authors: Fitzpatrick, Paul
Format: Others
Language:en_US
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/1969.1/ETD-TAMU-2010-08-8285