Gas-phase and Solution-phase Peptide Conformations Studied by Ion Mobility-mass Spectrometry and Molecular Dynamics Simulations

Gas-phase and Solution-phase Peptide Conformations Studied by Ion Mobility-mass Spectrometry and Molecular Dynamics Simulations

Ion mobility spectrometry (IMS) separates ions on the basis of ion-neutral collision cross-sections (CCS, [omega]), which are determined by the geometry or conformation of the ions. The size-based IM separation can be extended to distinguish conformers that have different shapes in cases where shape...

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Bibliographic Details
Main Author: Chen, Liuxi
Other Authors: Russell, David H.
Format: Others
Language:en_US
Published: 2012
Subjects:
ion mobility
mass spectrometry
peptide conformations
gas phase
molecular dynamics
gramicidin A
tryptophan zipper
electrospray
intergrated tempering sampling molecular dynamics
ITS
collision cross section
Online Access:http://hdl.handle.net/1969.1/ETD-TAMU-2012-08-11689

Internet

http://hdl.handle.net/1969.1/ETD-TAMU-2012-08-11689

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