Fluorescent-detected retrotranslocation of an endoplasmic reticulum - associated degradation (ERAD) substrate in a mammalian in vitro system
Secretory proteins that are unable to assemble into native proteins in the endoplasmic reticulum (ER) are transported back into the cytosol for degradation. Many cytosolic and ER resident proteins have been identified so far as being involved in this retrotranslocation process, but it is difficult t...
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Format: | Others |
Language: | en_US |
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2010
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Online Access: | http://hdl.handle.net/1969.1/ETD-TAMU-2019 http://hdl.handle.net/1969.1/ETD-TAMU-2019 |