Structural and functional investigation of human chemokines and applications of human chemokines in blocking HIV-1 entry
Chemokines are important mediators of leukocyte migration. Chemokines bind to G protein–coupled receptors (GPCR) and cause conformational changes that trigger intracellular signaling pathways involved in inflammation, injury healing, cancer, metastasis, and HIV infections. No direct structural infor...
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Format: | Others |
Language: | en_US |
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2010
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Online Access: | http://hdl.handle.net/1969.1/ETD-TAMU-2430 http://hdl.handle.net/1969.1/ETD-TAMU-2430 |