Structural and functional investigation of human chemokines and applications of human chemokines in blocking HIV-1 entry

Chemokines are important mediators of leukocyte migration. Chemokines bind to G protein–coupled receptors (GPCR) and cause conformational changes that trigger intracellular signaling pathways involved in inflammation, injury healing, cancer, metastasis, and HIV infections. No direct structural infor...

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Bibliographic Details
Main Author: Jin, Hongjun
Other Authors: LiWang, Patricia J.
Format: Others
Language:en_US
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1969.1/ETD-TAMU-2430
http://hdl.handle.net/1969.1/ETD-TAMU-2430