The role of p53 in normal development and teratogen-induced apoptosis and birth defects in mouse embryos

In the studies described in this dissertation, we investigated the roles of p53 in normal development, teratogen-induced apoptosis, and birth defects. In the first study, the activation of p53 and its target genes, p21, NOXA, and PUMA, were examined during neural tube closure in mouse embryos expose...

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Bibliographic Details
Main Author: Hosako, Hiromi
Other Authors: Mirkes, Philip E
Format: Others
Published: 2010
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