Incorporation of histidine-rich metal-binding sites onto small protein scaffolds: implications for imaging, therapeutics, and catalysis
Many histidine-rich sites in proteins bind transition metal ions such as Zn2+, natively. Such sites can encourage proper protein folding or allow access to enzymatic capabilities such as hydrolysis. Ru(II) and Tc(I) also bind to aromatic amines providing access to unique chemistries...
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| Format: | Others |
| Language: | English |
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University of Iowa
2008
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| Online Access: | https://ir.uiowa.edu/etd/37 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1222&context=etd |