Novel mechanisms for enzymatic regulation of phosphatidylcholine synthesis by proteolysis

Pulmonary surfactant is a critical surface-active substance consisting of dipalmitoylphosphatidylcholine (DPPtdCho) and key apoproteins that are produced and secreted into the airspace from alveolar type II epithelial cells. Surfactant deficiency leads to severe lung atelectasis, ventilatory impairm...

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Bibliographic Details
Main Author: Chen, Beibei
Other Authors: Shea, Madeline A.
Format: Others
Language:English
Published: University of Iowa 2008
Subjects:
Online Access:https://ir.uiowa.edu/etd/199
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1384&context=etd