Novel mechanisms for enzymatic regulation of phosphatidylcholine synthesis by proteolysis
Pulmonary surfactant is a critical surface-active substance consisting of dipalmitoylphosphatidylcholine (DPPtdCho) and key apoproteins that are produced and secreted into the airspace from alveolar type II epithelial cells. Surfactant deficiency leads to severe lung atelectasis, ventilatory impairm...
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Format: | Others |
Language: | English |
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University of Iowa
2008
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Online Access: | https://ir.uiowa.edu/etd/199 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1384&context=etd |