Regulation of nerve growth factor signaling by protein phosphatase 2A

The goal of this dissertation research is to determine novel regulatory mechanisms of neurotrophin signaling mediated by protein phosphatase 2A (PP2A). PP2A is a ubiquitous Ser/Thr phosphatase that removes phosphates from proteins to switch their activity on or off. The substrate specificity and sub...

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Bibliographic Details
Main Author: Van Kanegan, Michael J
Other Authors: Strack, Stefan
Format: Others
Language:English
Published: University of Iowa 2008
Subjects:
NGF
ERK
Online Access:https://ir.uiowa.edu/etd/279
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1464&context=etd