The recycling endosome is required for transport of retrograde toxins

Shiga toxin and cholera toxin are members of the AB5 family of protein exotoxins. The A subunit is the enzymatic subunit, whereas the pentameric B subunit binds cell surface receptors and carries the A subunit to the endoplasmic reticulum (ER) where it can be released into the cytosol. The B-subunit...

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Bibliographic Details
Main Author: McKenzie, Jenna Elyse
Other Authors: Sheff, David R.
Format: Others
Language:English
Published: University of Iowa 2009
Subjects:
Online Access:https://ir.uiowa.edu/etd/406
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1591&context=etd