The recycling endosome is required for transport of retrograde toxins
Shiga toxin and cholera toxin are members of the AB5 family of protein exotoxins. The A subunit is the enzymatic subunit, whereas the pentameric B subunit binds cell surface receptors and carries the A subunit to the endoplasmic reticulum (ER) where it can be released into the cytosol. The B-subunit...
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Language: | English |
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University of Iowa
2009
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Online Access: | https://ir.uiowa.edu/etd/406 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1591&context=etd |