Studies of proliferating cell nuclear antigen and its role in translesion synthesis
One major pathway to overcome DNA damage induced replication blocks is translesion DNA synthesis, which is the replicative bypass of DNA damage by non-classical polymerases. For the cell to utilize translesion synthesis the non-classical DNA polymerase is recruited to sites of DNA damage, and a poly...
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Language: | English |
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University of Iowa
2010
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Online Access: | https://ir.uiowa.edu/etd/668 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1853&context=etd |