Geranylgeranyl diphosphate synthase as a novel cancer therapeutic target

The isoprenoid biosynthetic pathway is targeted in the treatment of several diseases, including hypercholesteremia and bone related disorders. Farnesyl diphosphate (FPP) and geranylgeranyl diphosphate (GGPP) are isoprenoid biosynthetic pathway intermediates that are utilized during post-translationa...

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Bibliographic Details
Main Author: Dudakovic, Amel
Other Authors: Hohl, Raymond J.
Format: Others
Language:English
Published: University of Iowa 2010
Subjects:
Online Access:https://ir.uiowa.edu/etd/795
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1980&context=etd