Geranylgeranyl diphosphate synthase as a novel cancer therapeutic target
The isoprenoid biosynthetic pathway is targeted in the treatment of several diseases, including hypercholesteremia and bone related disorders. Farnesyl diphosphate (FPP) and geranylgeranyl diphosphate (GGPP) are isoprenoid biosynthetic pathway intermediates that are utilized during post-translationa...
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Format: | Others |
Language: | English |
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University of Iowa
2010
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Online Access: | https://ir.uiowa.edu/etd/795 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1980&context=etd |