Role of receptor ubiquitination in erythropoietin receptor signaling

Erythropietin (Epo), acting through its receptor (EpoR), is an essential hemotopietic growth factor that regulates the proliferation, differentiation, and survival of erythroid progenitor cells. Perturbations of Epo/EpoR function cause myeloproliferative disease, such as erythrocytosis, or myelodefi...

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Bibliographic Details
Main Author: Mayuzumi, Daisuke
Other Authors: Quelle, Frederick W.
Format: Others
Language:English
Published: University of Iowa 2010
Subjects:
Online Access:https://ir.uiowa.edu/etd/854
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=2039&context=etd