Structure-activity relationships for interactions of hydroxylated polychlorinated biphenyls with human hydroxysteroid sulfotransferase hSULT2A1

Industrial chemicals known as polychlorinated biphenyls (PCBs) were widely used for decades until their production was banned worldwide due to their persistence and toxicities to humans and other animals. Upon oxidative metabolism by cytochrome P450, hydroxylated metabolites of PCBs (OHPCBs) are for...

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Bibliographic Details
Main Author: Ekuase, Edugie Jennifer
Other Authors: Duffel, Michael W.
Format: Others
Language:English
Published: University of Iowa 2011
Subjects:
Online Access:https://ir.uiowa.edu/etd/959
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=2344&context=etd