Structure-activity relationships for interactions of hydroxylated polychlorinated biphenyls with human hydroxysteroid sulfotransferase hSULT2A1
Industrial chemicals known as polychlorinated biphenyls (PCBs) were widely used for decades until their production was banned worldwide due to their persistence and toxicities to humans and other animals. Upon oxidative metabolism by cytochrome P450, hydroxylated metabolites of PCBs (OHPCBs) are for...
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Language: | English |
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University of Iowa
2011
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Online Access: | https://ir.uiowa.edu/etd/959 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=2344&context=etd |