Dysregulation of CD40 signaling pathways in enhanced B cell activation and autoimmunity

CD40 signals are required for productive immune responses but also play a role in autoimmune disease pathogenesis. The major goal of this research was to investigate the contribution of two receptors to the development of autoimmune disease: (1) LMP1, an oncogenic EBV-encoded mimic of CD40 and (2) a...

Full description

Bibliographic Details
Main Author: Peters, Anna Louisa
Other Authors: Bishop, Gail
Format: Others
Language:English
Published: University of Iowa 2011
Subjects:
EBV
Online Access:https://ir.uiowa.edu/etd/1055
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=2440&context=etd