Dysregulation of CD40 signaling pathways in enhanced B cell activation and autoimmunity
CD40 signals are required for productive immune responses but also play a role in autoimmune disease pathogenesis. The major goal of this research was to investigate the contribution of two receptors to the development of autoimmune disease: (1) LMP1, an oncogenic EBV-encoded mimic of CD40 and (2) a...
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Format: | Others |
Language: | English |
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University of Iowa
2011
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Online Access: | https://ir.uiowa.edu/etd/1055 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=2440&context=etd |