Investigations in amine chemistry: Mn-Mediated radical addition approach toward gamma amino esters and synthetic studies of the tubulysins
Mn-Mediated radical addition has been developed within the Friestad laboratory as a versatile method toward addition to C=N bonds. N-Acylhydrazones generated by condensation between an aldehyde and an N-acylamine serves as the substrate toward radical addition. A bulky directed group attached with t...
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Language: | English |
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University of Iowa
2011
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Online Access: | https://ir.uiowa.edu/etd/1121 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=2505&context=etd |