Mn-mediated radical coupling toward synthesis of alpha, alpha-disubstituted alpha-amino esters and formal synthesis of quinine
Chiral alpha-branched amines are common substructures of bioactive synthetic targets such as alkaloids and amino acids. Direct asymmetric amine synthesis by addition to the C=N bond of carbonyl imino derivatives is promising and efficient to introduce the stereogenic center and carbon-carbon bond in...
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| Format: | Others |
| Language: | English |
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University of Iowa
2011
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| Online Access: | https://ir.uiowa.edu/etd/1150 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=2534&context=etd |