The effects of Med12 variation upon cell cycle progression and differential gene expression
MED12 is an X– chromosome member of the Mediator complex that is a key regulator of tissue specific gene expression and moderates intracellular signaling via multiple developmental pathways. Sequence variation in the carboxy– terminus of MED12, which contains a PQL and Opa domain, is associated with...
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Format: | Others |
Language: | English |
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University of Iowa
2011
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Online Access: | https://ir.uiowa.edu/etd/2787 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=2686&context=etd |