Spectral binding of multiple ortho substituted polychlorinated biphenyls and their 5-hydroxy metabolites to microsomal cytochrome P450 enzymes
Polychlorinated biphenyls (PCBs) are persistent organic pollutants that are carcinogenic and cause a variety of adverse health effects to the nervous, reproductive and endocrine systems. They bind to cytochrome P450 (CYP) enzymes to undergo phase I biotransformation to form hydroxylated metabolites....
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| Language: | English |
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University of Iowa
2011
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| Online Access: | https://ir.uiowa.edu/etd/2733 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=2713&context=etd |