Next generation monoclonal antibodies and their mechanisms of action against B-cell lymphomas

Next generation monoclonal antibodies (mAbs) are unique in that they are specifically designed to enhance their mechanisms of action, primarily complement fixation and antibody-dependent cellular cytotoxicity (ADCC). Recent studies suggest that complement-fixing properties of a mAb can counter its a...

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Bibliographic Details
Main Author: Peri, Delila
Other Authors: Weiner, George J.
Format: Others
Language:English
Published: University of Iowa 2012
Subjects:
Online Access:https://ir.uiowa.edu/etd/3367
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=3312&context=etd