Next generation monoclonal antibodies and their mechanisms of action against B-cell lymphomas
Next generation monoclonal antibodies (mAbs) are unique in that they are specifically designed to enhance their mechanisms of action, primarily complement fixation and antibody-dependent cellular cytotoxicity (ADCC). Recent studies suggest that complement-fixing properties of a mAb can counter its a...
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Language: | English |
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University of Iowa
2012
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Online Access: | https://ir.uiowa.edu/etd/3367 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=3312&context=etd |