Endothelial agonists stimulate VWF release in vitro and trigger TTP in vivo

Von Willebrand factor (VWF) is a plasma glycoprotein that can bind collagen at a wound site as well as circulating platelets. VWF forms high molecular weight multimers (>20,000 kDa). VWF can also form VWF strings that appear to be attached to the endothelial surface and are capable of binding pla...

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Bibliographic Details
Main Author: Schaeffer, Gilbert Van
Other Authors: Motto, David George
Format: Others
Language:English
Published: University of Iowa 2013
Subjects:
TTP
VWF
Online Access:https://ir.uiowa.edu/etd/5054
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=5054&context=etd