The role Of sirtuin3 in regulating mitochondrial superoxide metabolism in response to ionizing radiation in mouse embryonic fibroblasts.

Exposure of mammalian cells to ionizing radiation is believed to affect mitochondrial metabolism, which can lead to increased levels of superoxide (O2*-). Sirtuin3 (Sirt3) is a key mitochondrial protein deacetylase thought to play a significant role in the maintenance of mitochondrial integrity and...

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Bibliographic Details
Main Author: Mapuskar, Kranti Ashok
Other Authors: Spitz, Douglas Robert
Format: Others
Language:English
Published: University of Iowa 2013
Subjects:
Online Access:https://ir.uiowa.edu/etd/4688
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=5204&context=etd