The role Of sirtuin3 in regulating mitochondrial superoxide metabolism in response to ionizing radiation in mouse embryonic fibroblasts.
Exposure of mammalian cells to ionizing radiation is believed to affect mitochondrial metabolism, which can lead to increased levels of superoxide (O2*-). Sirtuin3 (Sirt3) is a key mitochondrial protein deacetylase thought to play a significant role in the maintenance of mitochondrial integrity and...
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Format: | Others |
Language: | English |
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University of Iowa
2013
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Online Access: | https://ir.uiowa.edu/etd/4688 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=5204&context=etd |