Improving lentiviral vector-mediated gene transfer by understanding cellular barriers
Cystic fibrosis (CF) is an autosomal recessive genetic disorder of which lung disease is the leading cause of morbidity and mortality. One attractive strategy for the treatment of CF lung disease is to directly deliver CF transmembrane conductance regulator gene to airway epithelia. Although promisi...
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| Language: | English |
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University of Iowa
2013
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| Online Access: | https://ir.uiowa.edu/etd/4709 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=5225&context=etd |