Regulation of dynamin-related protein 1-mediated mitochondrial fission by reversible phosphorylation and its contribution to neuronal survival following injury
Mitochondria are dynamic organelles that constantly undergo opposing fission and fusion events which impact many aspects of mitochondrial and cellular homeostasis including bioenergetic activity, calcium buffering and organelle transport. The large GTPase dynamin-related protein 1 (Drp1) acts as a m...
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| Language: | English |
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University of Iowa
2014
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| Online Access: | https://ir.uiowa.edu/etd/4756 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=5272&context=etd |