Retroviral mutagenesis in a newly developed myc transgenic mouse model of human B cell and plasma cell neoplasia
Three potential driver genes were identified by use of retroviral mutagenesis in the newly developed iMyc model of B cell malignancy. To do so, iMyc mice, which bear an inserted copy of c-Myc in the IgH locus, were treated with MOL4070LTR to favor the development of B cell malignancies. After tumor...
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| Format: | Others |
| Language: | English |
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University of Iowa
2013
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| Online Access: | https://ir.uiowa.edu/etd/1479 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=5555&context=etd |