NIAM, a novel activator of p53 and potential tumor suppressor

Cancer is the second leading cause of death in the United States, and it results from genetic alterations that promote the survival and proliferation of neoplastic cells. One of the most commonly disrupted cancer gene networks is the ARF-Mdm2-Tip60-p53 pathway. Inactivation of the ARF, Tip60 and p53...

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Bibliographic Details
Main Author: Reed, Sara Marie
Other Authors: Quelle, Dawn E.
Format: Others
Language:English
Published: University of Iowa 2015
Subjects:
p53
Online Access:https://ir.uiowa.edu/etd/1735
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=5787&context=etd