The flexible bivariate continual reassessment method
Early phase clinical trials during drug development are vital to the success of an investigational compound. In these phases, an important goal of a dose-finding study is the determination of a dose that is safe and/or effective. Dose-finding trials based on safety outcomes are typically among the f...
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| Language: | English |
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University of Iowa
2015
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| Online Access: | https://ir.uiowa.edu/etd/1917 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=5973&context=etd |