Inflammatory cytokine signaling contributes to Erlotinib resistance in head and neck squamous cell carcinoma

Resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) is a major obstacle in the success of head and neck cancer therapy. Despite efforts by several groups to understand the mechanisms of resistance to tyrosine kinase inhibitors such as erlotinib, there has been littl...

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Bibliographic Details
Main Author: Stanam, Aditya
Other Authors: Simons-Burnett, Andrean
Format: Others
Language:English
Published: University of Iowa 2016
Subjects:
Online Access:https://ir.uiowa.edu/etd/3194
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=6524&context=etd