Novel NAD+ metabolomic technologies and their applications to Nicotinamide Riboside interventions

Nicotinamide adenine dinucleotide (NAD+) is a cofactor in hydride transfer reactions and consumed substrate of several classes of glycohydrolyitc enzymes, including sirtuins. NAD+, its biosynthetic intermediates, breakdown products, and related nucleotides (the NAD metabolome) is altered in many met...

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Bibliographic Details
Main Author: Trammell, Samuel A.J.
Other Authors: Brenner, Charles, 1961-
Format: Others
Language:English
Published: University of Iowa 2016
Subjects:
Online Access:https://ir.uiowa.edu/etd/3203
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=6533&context=etd