Adoptive cancer immunotherapy with human Vγ2vδ2 T cells
Human γδ T cells expressing Vγ2Vδ2 TCRs monitor foreign- and self-prenyl pyrophosphate metabolites in isoprenoid biosynthesis to mediate immunity to microbes and tumors. Vγ2Vδ2 cells have been used for adoptive cancer immunotherapy with some partial and complete remissions. Most trials have used con...
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| Format: | Others |
| Language: | English |
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University of Iowa
2016
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| Online Access: | https://ir.uiowa.edu/etd/2247 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=6809&context=etd |