Dissection of molecular interactions of replication protein A in replication and repair

Replication protein A (RPA) is the major eukaryotic single-strand DNA (ssDNA) binding protein. RPA is composed of three subunits, RPA1, RPA2 and RPA3. RPA is essential for replication, repair, recombination, and checkpoint activation, and is required for maintaining genome integrity. In the cell, RP...

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Bibliographic Details
Main Author: Chen, Ran
Other Authors: Wold, Marc S.
Format: Others
Language:English
Published: University of Iowa 2015
Subjects:
Online Access:https://ir.uiowa.edu/etd/2192
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=6842&context=etd