Dissection of molecular interactions of replication protein A in replication and repair
Replication protein A (RPA) is the major eukaryotic single-strand DNA (ssDNA) binding protein. RPA is composed of three subunits, RPA1, RPA2 and RPA3. RPA is essential for replication, repair, recombination, and checkpoint activation, and is required for maintaining genome integrity. In the cell, RP...
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Language: | English |
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University of Iowa
2015
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Online Access: | https://ir.uiowa.edu/etd/2192 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=6842&context=etd |