Characterizing the contribution of hippo pathway dysregulation to sarcomagenesis
Sarcomas are cancers of mesenchymal origin. Though they comprise 15-20% of childhood cancers, and have a 5-year survival rate of 16% for metastatic disease, few targeted therapies exist, and the underlying mechanisms of their development are poorly understood. Transcriptional coactivators TAZ and YA...
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| Format: | Others |
| Language: | English |
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University of Iowa
2017
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| Online Access: | https://ir.uiowa.edu/etd/5769 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=7259&context=etd |