Generation and function of glucose-responsive insulin producing cells derived from human induced pluripotent stem cells
Type I diabetes (T1D) is caused by autoimmune destruction of pancreatic β-cells. Immediate consequences of T1D are severe weight loss, ketoacidosis and death unless insulin is administered. The long-term consequences of T1D are dysregulation of metabolism leading to cardiovascular complications, neu...
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Format: | Others |
Language: | English |
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University of Iowa
2015
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Online Access: | https://ir.uiowa.edu/etd/5808 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=7286&context=etd |