Generation and function of glucose-responsive insulin producing cells derived from human induced pluripotent stem cells

Type I diabetes (T1D) is caused by autoimmune destruction of pancreatic β-cells. Immediate consequences of T1D are severe weight loss, ketoacidosis and death unless insulin is administered. The long-term consequences of T1D are dysregulation of metabolism leading to cardiovascular complications, neu...

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Bibliographic Details
Main Author: Manzar, Gohar Shahwar
Other Authors: Zavazava, Nicholaus
Format: Others
Language:English
Published: University of Iowa 2015
Subjects:
Online Access:https://ir.uiowa.edu/etd/5808
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=7286&context=etd