Cognitive impairment and neuronal damage in Alzheimer's disease are malleable: occupational chlorpyrifos exposure exacerbates phenotypes, while the neuroprotective compound P7C3 ameliorates effects in a transgenic model of Alzheimer's disease.
Alzheimer’s disease (AD) is a devastating neurodegenerative disease that affects millions of peoples’ lives worldwide. While the consequences of AD are recognizable, the etiology is unclear. Gene-environment interactions have been implicated in the development of the disease, and exposure to organop...
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| Format: | Others |
| Language: | English |
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University of Iowa
2017
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| Online Access: | https://ir.uiowa.edu/etd/5871 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=7349&context=etd |