Chemical inhibitors of protein-protein interactions involved in G protein-mediated signaling events as potential therapeutics

G protein-coupled receptors (GPCRs) play a central role in numerous biological processes, from olfaction to vision to neurotransmission and more, leading to their classification as important drug targets. Signaling through GPCRs is carried out by a number of intracellular effector proteins, such as...

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Bibliographic Details
Main Author: Hayes, Michael Patrick
Other Authors: Roman, David L.
Format: Others
Language:English
Published: University of Iowa 2017
Subjects:
Online Access:https://ir.uiowa.edu/etd/5945
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=7426&context=etd