The Dm-Myb oncoprotein coordinates higher-order chromatin structure to potentiate expression of target genes as well as stabilize facultative heterocrhomatin

Myb is a proto-oncogene that when mutated causes leukemias and lymphomas in birds and mammals. Vertebrates contain three representatives of the Myb gene family consisting of A-, B- and c-Myb, all of which encode DNA-binding factors that are important for the proper expression of genes. Several studi...

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Bibliographic Details
Main Author: Santana, Juan F.
Other Authors: Manak, John R.
Format: Others
Language:English
Published: University of Iowa 2016
Subjects:
Online Access:https://ir.uiowa.edu/etd/6270
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=7602&context=etd