The role of protein dynamics on structure and function of Thymidylate synthase
The relationship between the protein motions, structure and catalytic activity is of contemporary interest in enzymology. Here, a broad array of kinetic techniques, site-directed mutagenesis, and methods involving isotopic labeling of substrates and proteins were used in studying thymidylate synthas...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | English |
| Published: |
University of Iowa
2014
|
| Subjects: | |
| Online Access: | https://ir.uiowa.edu/etd/6536 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=8035&context=etd |