Controlled presentation of cues during biomanufacturing to influence IDO mediated immune modulation by human MSCs

The goal of this project was to determine the key regulators of Mesenchymal Stromal Cell (MSC) potency as part of a cell-based therapy to treat inflammatory and autoimmune diseases. The immunomodulatory capacity of MSCs is dictated by multiple, interacting conditions that take place during the bioma...

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Bibliographic Details
Main Author: Boyt, Devlin Thomas
Other Authors: Ankrum, James A.
Format: Others
Language:English
Published: University of Iowa 2019
Subjects:
IDO
MSC
Online Access:https://ir.uiowa.edu/etd/6913
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=8325&context=etd