Characterization of the modulatory effects of alternative splicing on Cav1.4 Ca2+ channels

In synaptic terminals of retinal photoreceptors, Cav1.4 (L-type) Ca2+ channels mediate Ca2+ influx that promotes neurotransmitter release. Mutations in Cav1.4 are associated with multiple vision disorders including congenital stationary night blindness type 2(CSNB2). Cav1.4 undergoes weak Ca2+-depen...

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Bibliographic Details
Main Author: Williams, Brittany Nicole
Other Authors: Lee, Amy
Format: Others
Language:English
Published: University of Iowa 2019
Subjects:
Online Access:https://ir.uiowa.edu/etd/6883
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=8417&context=etd