Investigating the effects of structural modification of alkyl triphenylphosphonium compounds on mitochondrial uncoupling and accumulation

Investigating the effects of structural modification of alkyl triphenylphosphonium compounds on mitochondrial uncoupling and accumulation

Mitochondria are organelles present in eukaryotic cells that play a key role in regulating cells’ metabolic processes as well as cell death. The main function of mitochondria is to produce ATP, by oxidizing nutrients in a process called oxidative phosphorylation (OXPHOS). Besides this, mitochondria...

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Bibliographic Details
Main Author: Kulkarni, Chaitanya Aniruddha
Other Authors: Kerns, Robert J.
Format: Others
Language:English
Published: University of Iowa 2017
Subjects:
Mitochondria
OXPHOS
SAR
TPP
Triphenylphosphonium
Uncoupling
Pharmacy and Pharmaceutical Sciences
Online Access:https://ir.uiowa.edu/etd/6975
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=8476&context=etd

Internet

https://ir.uiowa.edu/etd/6975
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=8476&context=etd

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