Understanding multidrug resistance in Gram-negative bacteria -- A study of a drug efflux pump AcrB and a periplasmic chaperone SurA
Multiple drug resistance (MDR) has been a severe issue in treatment and recovery from infection.Gram-negative bacteria intrinsically exhibit higher drug tolerance than Gram-positive microbes. In this thesis, two proteins involved in Gram-negative bacterial MDR were studied, AcrB and SurA. Resistance...
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UKnowledge
2013
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Online Access: | http://uknowledge.uky.edu/chemistry_etds/17 http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1020&context=chemistry_etds |