A PREDICTIVE PROBABILITY INTERIM DESIGN FOR PHASE II CLINICAL TRIALS WITH CONTINUOUS ENDPOINTS

A PREDICTIVE PROBABILITY INTERIM DESIGN FOR PHASE II CLINICAL TRIALS WITH CONTINUOUS ENDPOINTS

Phase II clinical trials aim to potentially screen out ineffective and identify effective therapies to move forward to randomized phase III trials. Single-arm studies remain the most utilized design in phase II oncology trials, especially in scenarios where a randomized design is simply not practica...

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Bibliographic Details
Main Author: Liu, Meng
Format: Others
Published: UKnowledge 2017
Subjects:
Predictive Probability
Continuous Endpoints
Single-Arm
Phase II Trials
Interim Strategy
R package
Biostatistics
Clinical Trials
Online Access:http://uknowledge.uky.edu/epb_etds/15
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1014&context=epb_etds

Internet

http://uknowledge.uky.edu/epb_etds/15
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1014&context=epb_etds

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