THE ROLE OF THE L-TYPE CALCIUM CHANNEL AND ITS CARBOXYL-TERMINUS

THE ROLE OF THE L-TYPE CALCIUM CHANNEL AND ITS CARBOXYL-TERMINUS

In the heart, the primary role of the L-type calcium channel (LTCC) CaV1.2 is to conduct calcium into cardiomyocytes and initiate contraction. However, part of the CaV1.2 channel itself, the cleaved carboxyl-terminus (CCt) can also localize to the nucleus and regulate gene transcription. Therefore,...

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Bibliographic Details
Main Author: Byse, Miranda Jean
Format: Others
Published: UKnowledge 2010
Subjects:
L-type Calcium Channel
Calcium Channel Block
Transcription
Cardiac Development
Cardiac Hypertrophy
Medical Physiology
Online Access:http://uknowledge.uky.edu/gradschool_diss/20
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1019&context=gradschool_diss

Internet

http://uknowledge.uky.edu/gradschool_diss/20
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1019&context=gradschool_diss

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