DISSECTING THE BIOSYNTHESES OF GILVOCARCINS AND RAVIDOMYCINS

DISSECTING THE BIOSYNTHESES OF GILVOCARCINS AND RAVIDOMYCINS

Gilvocarcin V (GV) and ravidomycin (RMV) exhibit excellent antitumor activities in the presence of near-UV light at low concentration maintaining a low in vivo cytotoxicity. Although, the exact molecular mechanism for in vivo actions of these antibiotics has yet to be determined, a [2+2] cycloadditi...

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Bibliographic Details
Main Author: Kharel, Madan Kumar
Format: Others
Published: UKnowledge 2010
Subjects:
Gilvocarcin V
Ravidomycin V
enzymatic total synthesis
deoxysugar biosynthesis
dehydrogenase
Genetics
Medicine and Health Sciences
Molecular Biology
Online Access:http://uknowledge.uky.edu/gradschool_diss/96
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1100&context=gradschool_diss

Internet

http://uknowledge.uky.edu/gradschool_diss/96
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1100&context=gradschool_diss

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