THE ROLE OF P53 IN OXIDATIVE STRESS AND POLYGLUTAMINE NEUROTOXICITY
Polyglutamine expansion disorders are progressive neurodegenerative diseasesthat are caused by the pathological expansion of polyglutamine repeats. Huntington'sdisease (HD) is a polyglutamine disorder caused by the expansion of an existingpolyglutamine tract in a novel protein, Huntingtin (Htt)...
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| Format: | Others |
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UKnowledge
2003
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| Online Access: | http://uknowledge.uky.edu/gradschool_diss/266 http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1269&context=gradschool_diss |