THE ROLE OF NF-kB ACTIVATION IN HEPATIC TUMOR PROMOTION BY POLYCHOLORINATED BIPHENYLS (PCBs)

Polychlorinated biphenyls (PCBs) are nongenotoxic hepatic tumor promoters. PCBs have been shown to cause oxidative stress, but the exact mechanism by which PCBs exert their tumor promoting activity is not clear. In our study, PCB-153, a non-coplanar congener, caused a transient increase in hepatic N...

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Bibliographic Details
Main Author: Lu, Zijing
Format: Others
Published: UKnowledge 2002
Subjects:
Online Access:http://uknowledge.uky.edu/gradschool_diss/399
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1402&context=gradschool_diss