THE ROLE OF NF-kB ACTIVATION IN HEPATIC TUMOR PROMOTION BY POLYCHOLORINATED BIPHENYLS (PCBs)
Polychlorinated biphenyls (PCBs) are nongenotoxic hepatic tumor promoters. PCBs have been shown to cause oxidative stress, but the exact mechanism by which PCBs exert their tumor promoting activity is not clear. In our study, PCB-153, a non-coplanar congener, caused a transient increase in hepatic N...
Main Author: | |
---|---|
Format: | Others |
Published: |
UKnowledge
2002
|
Subjects: | |
Online Access: | http://uknowledge.uky.edu/gradschool_diss/399 http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1402&context=gradschool_diss |