GENETIC REGULATION OF HEMATOPOIETIC STEM CELL AGING

GENETIC REGULATION OF HEMATOPOIETIC STEM CELL AGING

It is well documented that both quantitative and qualitative changes in the murine hematopoietic stem cell (HSC) population occur with age. In mice, the effect of aging on stem cells is highly strain-specific, thus suggesting genetic regulation plays a role in HSC aging. In C57BL/6 (B6) mice, the HS...

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Bibliographic Details
Main Author: Oakley, Erin J.
Format: Others
Published: UKnowledge 2008
Subjects:
Hematopoietic Stem Cells
Aging
Genetic Regulation
QTL analysis
DNA damage
Medical Physiology
Medicine and Health Sciences
Online Access:http://uknowledge.uky.edu/gradschool_diss/659
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1662&context=gradschool_diss

Internet

http://uknowledge.uky.edu/gradschool_diss/659
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1662&context=gradschool_diss

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